https://clinicaltrials.gov/ct2/show/NCT04050410
Autonomic Determinants of POTS: Effects of Moxonidine on the Symptoms of Postural Orthostatic Tachycardia Syndrome (POTS)
Study Type : Interventional (Clinical Trial)
Estimated Enrollment : 48 participants
Allocation: Randomized
Intervention Model: Crossover Assignment
Intervention Model Description: Randomized, double-blind, placebo-controlled crossover
Masking: Double (Participant, Investigator)
Masking Description: Subject and investigator will be blinded. The randomization will be generated by the pharmacy. A staff member of the Autonomic Dysfunction Center who is not involved in the study will keep secretly the randomization blinding table for emergencies. Blinding will be broken for intermediate data analysis and in case of emergencies if necessary. The blinding will be broken at the end of statistical analysis for interpretation of results.
Primary Purpose: Other
Official Title: Autonomic Determinants of Postural Tachycardia Syndrome (Acute Pilot Study 1)
Actual Study Start Date : August 27, 2019
Estimated Primary Completion Date : July 31, 2024
Estimated Study Completion Date : December 31, 2025